Home Page of Michael A King, PhD
I am a Professor of Radiology at the University of Massachusetts Medical
School and direct the
Medical Physics Group within the
Division of Nuclear Medicine.
I can be reached at the address below:
Michael A. King, Ph.D.
Department of Radiology
Division of Nuclear Medicine
University of Massachusetts Medical School
55 Lake Ave North
Worcester, MA 01655
phone: (508) 856-4255
FAX: (508) 856-4275
- Correction for causes of image degradation in nuclear medicine such as
attenuation, distance-dependent spatial-resolution, and scatter.
- Tomographic image reconstruction for SPECT and PET.
- Assessment of image quality by task performance studies using
human and numerical observers.
- Quantitation of activity and assessement of function.
- Image segmentation and computer vision applications in nuclear medicine.
Above figure illustrates the degradation of a SPECT transverse slice
through the chest by photon attenuation, the acquisition of scattered photons,
and the finite imaging system spatial resolution.
- At left side is the true source distribution in this simulated image. Note
the shape edges and uniform intensity through the soft tissues, lungs, liver,
- Reconstruction of simulated projections from this distribution look
exactly like the source distribution in the absence of attenuation, scatter,
and system spatial resolution illustrating the success of reconstruction
methods with ideal data.
- At the left is the slice reconstructed from data which has included the
impact of attenuation, scatter, and system spatial resolution. Note the
variation in intensity in regions of uniform source distribution, and
distortation in shape.
- Bringing compensation strategies for such degradations into the clinical
use is the MAJOR GOAL of our research efforts.
- To learn more about SPECT compensation strategies for these degradations
you can read two PDF files with our reviews on this topic.
- Attenuation, Scatter, and Spatial Resolution
Compensation in SPECT, to appear in forth coming book EMISSION
TOMOGRAPHY: The Fundamentals of PET and SPECT, M. N. Wernick and J. N. Aarsvold,
eds., Academic Press. Updated: 23-May-2002
- An Overview of Attenuation and Scatter
of Planar and SPECT Data for Dosimetry Studies., Cancer Biotherapy
and Radiopharmaceuticals, submitted. Updated: 23-May-2002
- NIH R01-CA42165: Digital Restoration of
SPECT Images for Tumor Detection, M.A. King, Ph.D. PI, 2/1/01-1/31/06.
- NIH R01-EB01457: Patient Motion Detection and
correction in SPECT imaging, M.A. King, Ph.D. PI, 6/01/03-5/31/08.
- NIH R01-HL50349: Improved accuracy for SPECT
cardiac perfusion imaging, M.A. King, Ph.D. PI, 7/1/04-6/30/08.
- NIH R01-HL65425: 4D Image Restoration for Gated Cardiac SPECT, M. Wernick,
Ph.D. of IIT PI, M.A. King, Ph.D. PI U Mass Sub-Contract, 8/1/00- 7/31/04.
- Picker International, Grant for joint research on attenuation correction
and reconstruction of positron coincidence images. M.A. King, PI,